Crystal Structures of Archaemetzincin Reveal a Moldable Substrate-Binding Site
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چکیده
منابع مشابه
Crystal Structures of Archaemetzincin Reveal a Moldable Substrate-Binding Site
BACKGROUND Archaemetzincins are metalloproteases occurring in archaea and some mammalia. They are distinct from all the other metzincins by their extended active site consensus sequence HEXXHXXGXXHCX(4)CXMX(17)CXXC featuring four conserved cysteine residues. Very little is known about their biological importance and structure-function relationships. PRINCIPAL FINDINGS Here we present three cr...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0043863